What is the function of glyceraldehyde 3-phosphate dehydrogenase? A) oxidation of an aldehyde by NAD⁺ and formation of acyl-phosphate B) oxidation of an alcohol to an aldehyde by NAD⁺ C) dehydration and dephosphorylation of GAP D) hydrolysis of GAP E) removal of the 3-phosphoryl-group from GAP

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Quizplus · Accepted Answer

Glyceraldehyde 3-phosphate dehydrogenase catalyzes the oxidation of an aldehyde to a carboxylic acid by NAD+ (represented here as NAD⁺), coupled with the phosphorylation of the substrate, resulting in the formation of 1,3-bisphosphoglycerate, an acyl-phosphate. This is a key step in glycolysis where energy is conserved in the form of NADH and a high-energy phosphate bond.

What Is the Function of Glyceraldehyde 3-Phosphate Dehydrogenase