The major pathologic or structural changes associated with the physical presence of meconium in MAS include:
1) partially obstructed airways, air trapping, and alveolar hyperinflation.
2) pulmonary air leak syndromes (pneumomediastinum or pneumothorax).
3) totally obstructed airways and absorption atelectasis.
4) pulmonary edema and alveolar flooding.

Question

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The major pathologic changes associated with meconium aspiration syndrome (MAS) include partially and totally obstructed airways, air trapping, alveolar hyperinflation, and pulmonary air leak syndromes such as pneumomediastinum or pneumothorax. These changes can lead to significant respiratory distress in affected neonates.

The Major Pathologic or Structural Changes Associated with the Physical