The major pathologic or structural changes associated with cystic fibrosis include:
1) partial airway obstruction leading to hyperinflation.
2) bronchospasm.
3) thick, tenacious mucus.
4) total airway obstruction leading to atelectasis.

Question

Quizplus · Accepted Answer

Cystic fibrosis is characterized by the production of thick, tenacious mucus due to a defect in chloride transport. This leads to partial airway obstruction and hyperinflation, as well as total airway obstruction that can result in atelectasis. Bronchospasm is not a primary feature but can occur secondary to the other changes.

The Major Pathologic or Structural Changes Associated with Cystic Fibrosis