The enzyme phosphofructokinase (PFK) catalyzes a key step in glycolysis. PFK is inhibited by high levels of which of the following molecules?
A) glucose and NAD⁺
B) AMP and ATP
C) ATP and citrate
D) citrate and CO₂

Question

Quizplus · Accepted Answer

ATP and citrate are both high-energy molecules that indicate that the cell has sufficient energy stores and therefore does not need to proceed with glycolysis. When PFK is inhibited by ATP and citrate, glycolysis slows down, allowing the cell to conserve energy.

The Enzyme Phosphofructokinase (PFK) Catalyzes a Key Step in Glycolysis