When damaged or single-stranded DNA activates the RecA protein, the RecA protein stimulates the cleavage of LexA. This results in
A) repression of polymerase V and activation of endonuclease.
B) activation of the Hfr system.
C) derepression of the SOS system.
D) increased transduction and recombination.

Question

Quizplus · Accepted Answer

The cleavage of LexA by RecA protein results in derepression of SOS system. The SOS response increases DNA repair and mutagenesis in response to DNA damage. This is important for cell survival in stressful conditions. Choice A is not correct as the activation of endonuclease and repression of polymerase V is a result of the SOS response, not the cleavage of LexA. Choice B is incorrect as the Hfr system is unrelated to DNA damage response. Choice D is incorrect as increased transduction and recombination are not a direct consequence of the RecA-mediated cleavage of LexA.

When Damaged or Single-Stranded DNA Activates the RecA Protein, the RecA