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A Mutant You Made in the Laboratory with 5-Bromouracil Suddenly

Question 86

Essay

A mutant you made in the laboratory with 5-bromouracil suddenly regains the wild-type phenotype. You discuss this phenomenon with your advisor and colleagues, and they suggest you try transposon mutagenesis to avoid this problem and create stable mutants. Why would mutants created with 5-bromouracil be more likely to regain the wild-type phenotype than mutants created via transposon mutagenesis?

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Because a point mutation involves only a...

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