Thermostable proteins tend to have additional features that improve thermostability. Which of the following is NOT one of these features?
A) increased ionic interactions on the protein surfaces
B) highly hydrophilic cores
C) decreased tendency of the protein to unfold
D) highly hydrophobic cores

Question

Quizplus · Accepted Answer

Thermostable proteins typically have highly hydrophobic cores rather than highly hydrophilic cores. This hydrophobic core helps in stabilizing the protein structure at high temperatures by reducing the entropy gain upon unfolding, thus making the protein less likely to unfold.

Thermostable Proteins Tend to Have Additional Features That Improve Thermostability