Antigen receptors can directly connect to signal transduction pathways because immunoglobulins and TCRs have very small cytoplasmic domains.

Question

Quizplus · Accepted Answer

While it is true that immunoglobulins and TCRs have small cytoplasmic domains, they do not directly connect to signal transduction pathways. Instead, they require the assistance of specialized signaling molecules such as CD3 and Igα/Igβ (in the case of TCRs) or Igα/Igβ and the B-cell receptor complex (in the case of immunoglobulins) to initiate signal transduction.

Antigen Receptors Can Directly Connect to Signal Transduction Pathways Because