In B cell selection and tolerance, if no signal is generated from ________ cells, the B cells remain unresponsive.
A) TC
B) TH
C) B₇
D) CD₂₈

Question

Quizplus · Accepted Answer

B cells require signals from helper T cells (TH) in order to become activated and proliferate. If no signal is generated from TH cells, the B cells remain unresponsive. TC cells are T cytotoxic cells and are not involved in activating B cells. B7 is a co-stimulatory molecule expressed on antigen-presenting cells and is important for activating T cells. CD28 is a co-stimulatory molecule on T cells that interacts with B7 to enhance T cell activation. CD28 is not directly involved in B cell selection and tolerance.

In B Cell Selection and Tolerance, If No Signal Is