Each immunoglobulin or TCR interacts with a single antigen, but MHC proteins can interact with more than one antigen.

Question

Quizplus · Accepted Answer

MHC proteins are able to interact with a variety of antigens due to their structural variability and ability to bind peptides of various sizes and shapes. In contrast, each immunoglobulin or TCR typically binds specifically to a single antigen via its unique binding site.

Each Immunoglobulin or TCR Interacts with a Single Antigen, but MHC