You Tell Your Patient's Parents That Muscle Weakness Is Frequently

You tell your patient's parents that muscle weakness is frequently a sign of mitochondrial disease because 

A) muscle cells require a lot of energy, which is provided by the many mitochondria within these cells.
B) muscles require a lot of energy which is provided by the mitochondrial DNA of the red blood cells.
C) people with mitochondrial disease seldom eat sufficient protein to fuel the mitochondria.
D) the diseased mitochondria release toxins into the muscles of the affected people, weakening them.
E) the diseased mitochondria consume all the energy that is supposed to be directed to the muscle cells.