Intercalating agents
A) act during RNA synthesis AND often result in frameshift mutations.
B) act during RNA synthesis AND change the hydrogen bonding properties of nucleotides.
C) act during DNA synthesis AND often result in frameshift mutations.
D) change the hydrogen bonding properties of nucleotides AND always result in nonsense mutations.
E) act during DNA synthesis AND always result in nonsense mutations.

Question

Quizplus · Accepted Answer

Intercalating agents are compounds that insert themselves between the stacked bases of double-stranded DNA, which causes the helix to unwind and creates gaps in the strands during replication. This results in errors during DNA synthesis, which can lead to frameshift mutations. Intercalating agents do not generally act during RNA synthesis, and they do not always result in nonsense mutations.

Intercalating Agents