A Researcher Gains Support of the Medical Staff, the Nursing

A researcher gains support of the medical staff, the nursing staff, and the nurse manager of a cardiothoracic ICU within a prestigious private hospital, aligned with a teaching institution. A research proposal, concerning ambulation patterns after bypass surgery, is approved by the Human Subjects Committee. Federal funding is obtained. Just before data collection is to begin, the hospital is sold to a large university with a medical school, the nurse manager is replaced with a manager from another hospital in the corporation, and there is a 30% staff turnover. Which of the following factors are expected to affect study feasibility in a negative manner?

A) Most of the newly hired nurses are BSNs and newly graduated.
B) The new manager grudgingly allows the research to proceed but makes it clear that she will not support subsequent research until the unit is more stable.
C) Fewer patients come to this hospital now for bypass surgery, going instead to its sister hospital across town.
D) Two of the research assistants, who were already trained, take jobs elsewhere.
E) Staff nurses disliked the old manager and like the replacement one.