Which of the following are most susceptible to complement lysis?
A) Gram-positive bacteria
B) Gram-negative bacteria
C) Bacteriophages
D) Prions
E) Acid-fast bacteria

Question

Quizplus · Accepted Answer

Gram-negative bacteria are the most susceptible to complement lysis as they have a thinner peptidoglycan layer in their cell wall, which makes them more vulnerable to osmotic stress caused by the formation of the membrane attack complex (MAC) during complement activation. Gram-positive bacteria have a thicker peptidoglycan layer that provides more resistance to complement lysis. Bacteriophages, prions, and acid-fast bacteria are not susceptible to complement lysis.

Which of the Following Are Most Susceptible to Complement Lysis