Please select the correct sequence for the steps of phagocytosis:
1) Conditions in the phagosome change, increasing its antimicrobial activities.
2) The phagocytic cell binds microbial invaders and engulfs them, internalizing them in a phagosome.
3) Phagocytic cells are recruited to the site of an injury by chemoattractants.
4) Within the phagolysosome, various factors work together to destroy an engulfed invader.
5) The phagosome fuses with enzyme-filled lysosomes, forming a phagolysosome.
A) 1, 2, 3, 4, 5
B) 2, 4, 3, 5, 1
C) 3, 2, 1, 5, 4
D) 1, 3, 5, 2, 4
E) 1, 5, 2, 4, 3

Question

Please select the correct sequence for the steps of phagocytosis:
1) Conditions in the phagosome change, increasing its antimicrobial activities.
2) The phagocytic cell binds microbial invaders and engulfs them, internalizing them in a phagosome.
3) Phagocytic cells are recruited to the site of an injury by chemoattractants. 
4) Within the phagolysosome, various factors work together to destroy an engulfed invader.
5) The phagosome fuses with enzyme-filled lysosomes, forming a phagolysosome.
A) 1, 2, 3, 4, 5
B) 2, 4, 3, 5, 1
C) 3, 2, 1, 5, 4
D) 1, 3, 5, 2, 4
E) 1, 5, 2, 4, 3

Quizplus · Accepted Answer

The correct sequence for phagocytosis starts with the recruitment of phagocytic cells to the site of injury (3), followed by the binding and engulfment of microbial invaders (2). After engulfment, conditions within the phagosome change to increase antimicrobial activities (1). The phagosome then fuses with lysosomes to form a phagolysosome (5), where various factors work together to destroy the invader (4).

Please Select the Correct Sequence for the Steps of Phagocytosis