The Fc region on IgG
A) interacts with complement AND contains a variable region.
B) attaches to receptors on macrophages AND contains a variable region.
C) interacts with complement AND attaches to receptors on macrophages.
D) reacts with and coats the antigen AND interacts with complement.
E) reacts with and coats the antigen AND attaches to receptors on macrophages.

Question

The Fc region on IgG
A) interacts with complement AND contains a variable region.
B) attaches to receptors on macrophages AND contains a variable region.
C) interacts with complement AND attaches to receptors on macrophages.
D) reacts with and coats the antigen AND interacts with complement.
E) reacts with and coats the antigen AND attaches to receptors on macrophages.

Quizplus · Accepted Answer

The Fc region of IgG is known for its ability to interact with complement proteins, which are part of the immune system's way of enhancing the ability to clear pathogens. It also has the ability to attach to receptors on macrophages, which are cells that can engulf and destroy pathogens. The Fc region does not contain a variable region; that is a characteristic of the Fab region of antibodies. The Fc region also does not directly react with and coat the antigen; this is the role of the antibody's antigen-binding sites, located in the Fab region.

The Fc Region on IgG