Which of the Following Is the Definition of Clonal Selection

Which of the following is the definition of clonal selection?

A) The killing of antibody-coated target cells by natural killer cells, granulocytes, or macrophages.
B) The process in which a lymphocyte's antigen receptor binds to an antigen, allowing the lymphocyte to multiply.
C) The process that allows a B cell to change the antibody class it is programmed to make.
D) The immune response that protects the mucous membranes, which involves secretory IgA.
E) The generation of diversity in antigen specificity through rearrangement of gene segments.