The most significant multilateral agreement signed since World War II was the Nuclear Non-proliferation Treaty of 1968.

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The Nuclear Non-proliferation Treaty (NPT) is a landmark international treaty that was signed in 1968. It is designed to prevent the spread of nuclear weapons and to promote cooperation in the peaceful uses of nuclear energy. The NPT has been signed by over 190 countries, making it one of the most widely adhered to treaties in history.

The Most Significant Multilateral Agreement Signed Since World War II