
Select the True statement regarding clostridial myonecrosis.
A) Clostridium perfringens infects healthy tissue and grows easily in well oxygenated tissues.
B) The causative agent produces α-toxin, an A-B toxin that destroys lecithin in host cell membranes, leading to cell lysis.
C) Hyperbaric chambers may be used to treat patients with gangrene-high levels of O₂ reduce anaerobic conditions in the tissues.
D) Prevention of clostridial myonecrosis can be achieved with the DCTaP vaccine.
E) C. perfringens is an endospore-forming organism, and produces large number of spores in wounds or cultures.
Correct Answer:
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