Why might it be more difficult to prepare a vaccine against noroviruses than against rotaviruses?
A) We haven't been able to culture noroviruses in a lab setting yet. Without a starting culture, we can't create a vaccine.
B) Noroviruses are RNA viruses, where rotaviruses are DNA viruses. RNA viruses mutate far more easily than DNA viruses, so we COULD make a vaccine, but it would be rendered useless fairly quickly as the virus mutates.
C) We lack a proper culturing method for large-scale production of target cells for norovirus, whereas we have such a system for the target cells of rotaviruses. Without a system to get large numbers of target cells, we can't produce a vaccine.
D) Norovirus is much more infectious than rotavirus. As such, it's much harder to work with safety. This makes production of a vaccine too dangerous and unpredictable.
E) This question is misleading. It has been relatively simple to create vaccines against both of these virus types.

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The Answer of Why might it be more difficult to prepare a vaccine against noroviruses than against rotaviruses?
A) We haven't been able to culture noroviruses in a lab setting yet. Without a starting culture, we can't create a vaccine.
B) Noroviruses are RNA viruses, where rotaviruses are DNA viruses. RNA viruses mutate far more easily than DNA viruses, so we COULD make a vaccine, but it would be rendered useless fairly quickly as the virus mutates.
C) We lack a proper culturing method for large-scale production of target cells for norovirus, whereas we have such a system for the target cells of rotaviruses. Without a system to get large numbers of target cells, we can't produce a vaccine.
D) Norovirus is much more infectious than rotavirus. As such, it's much harder to work with safety. This makes production of a vaccine too dangerous and unpredictable.
E) This question is misleading. It has been relatively simple to create vaccines against both of these virus types.

Why Might It Be More Difficult to Prepare a Vaccine