Over Time, Humans Have Become Increasingly Dependent on Which of the Following

Over time, humans have become increasingly dependent on which of the following in order to cope with the range of environments they have occupied in time and space?

A) a holistic and comparative approach to problem solving
B) social institutions, such as the state, that coordinate collective action
C) technological means of adaptation, such as the creation of virtual worlds that allow us to escape from day-to-day reality
D) biological means of adaptation, mostly thanks to advanced medical research
E) cultural means of adaptation