The Following Patients Take a Benzodiazepine Drug at the Same

The following patients take a benzodiazepine drug at the same time. The effect of this drug is likely to last longest in which patient?

A) Chad, who has a cytochrome P450 polymorphism, causing decreased activity of these enzymes
B) Heather, who has higher than normal levels of GABA receptors
C) Erwin, who has higher than normal levels of cytochrome P450 enzymes
D) Luisa, who has a GABA_A receptor polymorphism, causing a stronger binding affinity for benzodiazepines