How May SNRIs Facilitate a Reduction in Anxiety

How may SNRIs facilitate a reduction in anxiety?

A) Inhibition of postsynaptic norepinephrine receptors leads to the eventual sensitization of β₁ adrenoceptors.
B) Inhibition of postsynaptic norepinephrine receptors leads to the eventual desensitization of β₁ adrenoceptors.
C) Activation of postsynaptic norepinephrine receptors leads to the eventual sensitization of β₁ adrenoceptors.
D) Activation of postsynaptic norepinephrine receptors leads to the eventual desensitization of β₁ adrenoceptors.