Why is the selective serotonin reuptake inhibitor (SSRI) zimelidine (Zelmid) no longer in clinical use and instead, the SSRI fluoxetine (Prozac) so widely prescribed?
A) Zelmid has a very low binding affinity for selective serotonin reuptake inhibitors; Prozac has a very strong binding affinity.
B) Zelmid was withdrawn from the market because of adverse effects; Prozac is one of the safest antidepressants.
C) Zelmid was found to increase norepinephrine levels in addition to serotonin; Prozac selectively increases serotonin levels.
D) Zelmid is habit forming; Prozac is not habit forming.
Correct Answer:
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