Why does the antidepressant drug bupropion provide an important exception to the serotonin hypothesis of depression?

Question

Quizplus · Accepted Answer

Bupropion works by increasing the release of dopamine and norepinephrine, two neurotransmitters, without significantly affecting serotonin levels. This mechanism of action is different from many other antidepressants that primarily target serotonin, thus providing an important exception to the serotonin hypothesis of depression, which suggests that depression is primarily caused by a deficiency in serotonin.

Why Does the Antidepressant Drug Bupropion Provide an Important Exception