Endogenous and exogenous opioids produce reinforcing effects by affecting ____ neurotransmission.
A) dopamine and GABA
B) dopamine and neuropeptide
C) norepinephrine and GABA
D) norepinephrine and neuropeptide

Question

Quizplus · Accepted Answer

Endogenous and exogenous opioids produce reinforcing effects primarily by affecting dopamine and GABA neurotransmission. They modulate the release of dopamine, a key neurotransmitter in the reward pathway, by inhibiting GABAergic neurons that normally inhibit dopamine release. This leads to an increase in dopamine levels, contributing to the reinforcing effects of opioids.

Endogenous and Exogenous Opioids Produce Reinforcing Effects by Affecting ____