How do opioids affect nociceptive signaling sent via C and Aδ axon terminals?
A) By increasing both glutamate and substance P release
B) By decreasing both glutamate and substance P release
C) By increasing glutamate release and decreasing substance P release
D) By decreasing glutamate release and increasing substance P release

Question

Quizplus · Accepted Answer

Opioids decrease nociceptive signaling by reducing the release of neurotransmitters such as glutamate and substance P from C and Aδ axon terminals, which are involved in transmitting pain signals to the brain.

How Do Opioids Affect Nociceptive Signaling Sent Via C and Aδ