Alexis takes the antianxiety drug buspirone. Before it reaches its site of action, 90% of the buspirone is metabolized, greatly reducing the amount of drug available for its biological effects. What is this process termed?

Question

Quizplus · Accepted Answer

This process is known as first-pass metabolism, which occurs when a drug is metabolized at a specific location in the body that results in a reduced concentration of the active drug upon reaching its site of action, often occurring in the liver.

Alexis Takes the Antianxiety Drug Buspirone