Dr. Ambroise is developing a drug to help promote axonal regeneration following brain injury. What might be an effective mechanism of action for Dr. Ambroise's drug?
A) Inhibit BDNF production.
B) Block uptake of neurotrophin-3.
C) Break down proteoglycans.
D) Increase production of semaphorin 3.

Question

Quizplus · Accepted Answer

Breaking down proteoglycans can be an effective mechanism because proteoglycans in the extracellular matrix can inhibit axonal growth. By breaking them down, the drug could potentially promote axonal regeneration following brain injury.

Dr Ambroise Is Developing a Drug to Help Promote Axonal