If drug A has an ED₅₀ value of 12.0 mg/kg, and drug B has an ED₅₀ value of 4.0 mg/kg, what can we say about the potencies of these drugs? A) Drug A is three times more potent than drug B. B) Drug A is eight times more potent than drug B. C) Drug B is three times more potent than drug A. D) Drug B is eight times more potent than drug A.

Question

Quizplus · Accepted Answer

The lower the ED₅₀ value, the less of the drug is needed to achieve a certain effect, indicating higher potency. Therefore, since drug B requires only 4.0 mg/kg compared to drug A's 12.0 mg/kg to achieve the same effect, drug B is three times more potent than drug A.

If Drug a Has an ED50 Value of 12

If Drug a Has an ED₅₀ Value of 12