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A Patient Who Takes Levodopa/carbidopa for Parkinson Disease Reports Periods

Question 19

Multiple Choice

A patient who takes levodopa/carbidopa for Parkinson disease reports periods of lost drug effect lasting from minutes to several hours with no relationship to the timing of drug administration. What course of action will the provider take?


A) Prescribe a COMT inhibitor, such as entacapone.
B) Add the DA-releasing agent amantadine to the regimen.
C) Prescribe a direct-acting dopamine agonist.
D) Shorten the dosing interval of levodopa/carbidopa.

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