A patient takes a drug that is metabolized by CYP3A4 isoenzymes. If a CYP3A4 inducing drug is prescribed, what drug adjustment may be necessary to maintain a therapeutic level of CYP3A4 substrate?

Question

Quizplus · Accepted Answer

CYP3A4 inducers increase the metabolism of drugs metabolized by CYP3A4, potentially lowering their plasma levels. To maintain therapeutic levels of the CYP3A4 substrate, increasing its dosage may be necessary.

A Patient Takes a Drug That Is Metabolized by CYP3A4