A patient experiences an acute gouty episode despite taking nonsteroidal antiinflammatory drugs for several months. The prescriber and patient had planned to begin therapy with probenecid. What effect will the acute episode have on the patient's planned medication therapy?

Question

Quizplus · Accepted Answer

Probenecid therapy for gout is typically delayed until an acute episode has subsided because initiating probenecid during an acute attack can worsen the symptoms. Probenecid works by increasing the excretion of uric acid, but during an acute attack, the focus is on reducing inflammation and pain, not on altering uric acid excretion.

A Patient Experiences an Acute Gouty Episode Despite Taking Nonsteroidal