What is the likely explanation when individuals with cystathionine-synthase deficiency do not respond to treatment by cofactor supplementation?
A) They have a dominant negative mutation
B) They have a recessive mutation
C) They lack residual cystathionine synthase activity
D) The level of vitamin supplementation required to stimulate their cystathionine synthase is toxic
E) The cofactor binding site is mutated
Correct Answer:
Verified
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