Which of the following is a possible consequence of a nonsense mutation?
A) Dominant negative mutation
B) Truncated protein
C) No translation
D) Protein instability
E) All of the above

Question

Quizplus · Accepted Answer

Nonsense mutations result in a premature stop codon, which can lead to a truncated protein (B), potentially causing protein instability (D) due to misfolding or incomplete functional domains. While not directly causing no translation (C), the effect is a significantly shortened protein, which might not be functional. A dominant negative mutation (A) can occur if the truncated protein interferes with the function of the wild-type protein, thus all options are possible consequences.

Which of the Following Is a Possible Consequence of a Nonsense