To do high resolution banding of chromosomes, what change to the procedure must be made relative to normal G-banding?
A) Use more cells
B) Lengthen the staining procedure
C) Amplify the chromosomes
D) Use a more sensitive stain
E) Arrest the cells earlier in mitosis

Question

Quizplus · Accepted Answer

High resolution banding of chromosomes requires arresting the cells earlier in mitosis, specifically in the prophase or prometaphase stages, rather than the metaphase. This allows for a greater expansion of the chromosomes, making more bands visible and thus increasing resolution.

To Do High Resolution Banding of Chromosomes, What Change to the Procedure