Why Is It Important That Synthesis of Globin Chains and Heme

Why is it important that synthesis of globin chains and heme be balanced in the RBCs?

A) Excess concentration of protoporphyrin increases bilirubin in plasma.
B) An excess of one of the components of hemoglobin decreases RBC survival.
C) An excess of one of the components of hemoglobin increases RBC survival leading to an eventual elevated RBC count.
D) An excess of globin chains significantly decreases the concentration of globin chain messenger ribonucleic acid (mRNA) in the developing RBCs.