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A Person with Familial Hypercholesterolemia Is Participating in an Ex

Question 36

Multiple Choice

A person with familial hypercholesterolemia is participating in an ex vivo gene therapy trial. The procedure involves


A) infecting a portion of the person's liver with a retrovirus containing a normal gene for a cholesterol receptor.
B) spraying the normal gene for the cholesterol receptor into the nose.
C) insertion of the cholesterol receptor gene into a virus, then injecting the virus into the person.
D) removing a piece of the person's liver, infecting it with a retrovirus containing the normal cholesterol receptor gene, and replacing the liver cells following treatment.
E) transplanting a normal liver into the individual.

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