Which of the following is true of ineffective erythropoiesis?

Question

Quizplus · Accepted Answer

RBC production in the bone marrow is increased in ineffective erythropoiesis (decreased M:E ratio).However,production is defective,and many of the red cells are destroyed before leaving the marrow.Thus release of RBCs to peripheral blood is decreased.Although survival of these RBCs in circulation may be slightly shortened from the normal of 120 days,it is not significant (the increased rate of production in the marrow could fully compensate for the slight shortening if the red cells were all released to circulation).Lymphopenia is not characteristic of these anemias.

Which of the Following Is True of Ineffective Erythropoiesis