You Overhear Two Psychopharmacologists Arguing About the Relative Pros and Cons

You overhear two psychopharmacologists arguing about the relative pros and cons associated with drug therapies targeting depression and anxiety. Which of the following would you be likely to overhear listed as an example of a common disadvantage of anti-anxiety drugs like sedatives?

A) they must be taken consistently for at least 6 weeks before they have a therapeutic effect
B) they do not have an effect on most people
C) they can result in physical dependence
D) we don't understand how they work
E) they are only effective in children