Maria had suffered some brain damage to her suprachiasmatic nucleus. Most likely, she would experience some problems with

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The suprachiasmatic nucleus is primarily responsible for controlling circadian rhythms, which are the physical, mental, and behavioral changes that follow a 24-hour cycle, affecting sleep patterns among other functions. Damage to this area would most likely disrupt these rhythms.

Maria Had Suffered Some Brain Damage to Her Suprachiasmatic Nucleus