An autopsy is performed at the request of the family after the death of an 89-year-old man. During sectioning of the brain, the substantia nigra is noted to have significant degeneration in the area of the pars compacta. This man most likely suffered from which of the following?
A) Foville's syndrome
B) Tourette's syndrome
C) Wilson's disease
D) Parkinson's disease
E) Huntington's disease

Question

Quizplus · Accepted Answer

Degeneration of the substantia nigra, particularly in the pars compacta region, is a hallmark pathological feature of Parkinson's disease. This condition leads to a deficiency in dopamine, contributing to the classic symptoms of bradykinesia, resting tremor, rigidity, and postural instability.

An Autopsy Is Performed at the Request of the Family