Hypophosphatemia (vitamin D-resistant rickets)is inherited as a sex-linked dominant trait. The relevant gene is found on the X chromosome. What is the expected outcome of a cross between a homozygous recessive woman and a man with hypophosphatemia?
A)All of their daughters and none of their sons exhibit hypophosphatemia.
B)Fifty percent of their daughters and fifty percent of their sons exhibit hypophosphatemia.
C)All of their sons and none of their daughters exhibit hypophosphatemia.
D)Twenty-five percent of their offspring exhibit hypophosphatemia.

Question

Quizplus · Accepted Answer

Since the trait is X-linked dominant, all daughters will inherit the affected X chromosome from their father and exhibit hypophosphatemia, while none of the sons will inherit the affected X chromosome from their mother and will not exhibit the trait.

Hypophosphatemia (Vitamin D-Resistant Rickets)is Inherited as a Sex-Linked Dominant Trait