In amyotrophic lateral sclerosis (also known as Lou Gehrig's disease), the cells that send messages from the brain to muscles, also known as _____, begin to break down, resulting in progressive movement impairments.

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In amyotrophic lateral sclerosis (ALS), the primary cells affected are the efferent neurons, which are responsible for sending signals from the brain and spinal cord to muscles, initiating movement. This leads to the progressive movement impairments seen in the disease.

In Amyotrophic Lateral Sclerosis (Also Known as Lou Gehrig's Disease)