Scenario
In sickle cell disease (SCD) , a mutation in hemoglobin causes deoxygenated hemoglobin to stick together in long chains, which in turn distorts red blood cells into an elongated, sickle (crescent) shape.
-In a person with SCD, where would red blood cells with a sickle shape be LEAST likely to be found?

Question

Quizplus · Accepted Answer

Red blood cells with a sickle shape are least likely to be found in the pulmonary veins because these veins carry oxygenated blood from the lungs to the heart. In the presence of oxygen, hemoglobin is less likely to polymerize and cause sickling.

Scenario In Sickle Cell Disease (SCD), a Mutation in Hemoglobin Causes