During active disease states, circulating autoantibodies directed toward a protein known as desmoglein 3 in skin and mucosa epithelium are seen in which of the following?

Question

Quizplus · Accepted Answer

Pemphigus vulgaris is an autoimmune disease characterized by the presence of circulating autoantibodies directed against desmoglein 3, a protein critical for cell-to-cell adhesion in the skin and mucosal epithelium. This leads to blistering of the skin and mucous membranes.

During Active Disease States, Circulating Autoantibodies Directed Toward a Protein