Which is a disorder that causes a severe birth defect that culminates in death by the age of 5 years?

Name: Which is a disorder that causes a severe birth defect that culminates in death by the age of 5 years?
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Tay Sachs is a genetic disorder that causes a severe birth defect and results in death by the age of 5 years. Down syndrome, Edwards syndrome, and Patau syndrome can also cause birth defects, but they do not typically result in death at such a young age.

Which Is a Disorder That Causes a Severe Birth Defect