AD cannot be detected on most scans, but autopsy reveals a deficit in brain presynaptic cholinergic systems.

Question

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Alzheimer's Disease (AD) is characterized by a deficit in brain presynaptic cholinergic systems, which is often confirmed through autopsy. While neuroimaging techniques can identify structural and functional changes in the brain associated with AD, the specific deficit in cholinergic systems is typically not detectable through most scans during life.

AD Cannot Be Detected on Most Scans, but Autopsy Reveals