Suppose that the pH of the matrix was significantly lower than the inner mitochondrial space. How would ATP synthase function differently?

Question

Quizplus · Accepted Answer

ATP synthase typically functions by utilizing the proton gradient between the intermembrane space and the matrix of mitochondria, with a higher concentration of protons in the intermembrane space driving the synthesis of ATP from ADP and inorganic phosphate. If the pH of the matrix were significantly lower (indicating a higher concentration of protons in the matrix than in the intermembrane space), the proton gradient would be reversed. This reversal would lead ATP synthase to function in the opposite direction, hydrolyzing ATP to form ADP and inorganic phosphate, instead of synthesizing ATP.

Suppose That the PH of the Matrix Was Significantly Lower