What is the decline in the occurrence of sickle cell anemia in the American population most likely the result of?

Question

Quizplus · Accepted Answer

The decline in sickle cell anemia in the American population is most likely due to a decline in the occurrence of malaria in the United States. Sickle cell trait provides a survival advantage in regions where malaria is prevalent, leading to higher frequencies of the trait in those populations. As malaria became less common in the U.S., the selective pressure for sickle cell trait decreased, leading to a decline in its occurrence.

What Is the Decline in the Occurrence of Sickle Cell